Postoperative comparison of four perioperative analgesia
protocols in dogs undergoing stifle joint surgery
Kerrie A.
Lewis, DVM, MS;
Richard M. Bednarski, DVM, MS;
Turi K. Aarnes, DVM, MS;
Jonathan
Dyce, MA, VetMB; John A. E. Hubbell, DVM, MS
(J Am Vet
Med Assoc 2014;244:1041–1046)
Summary
In this study the authors compared 4
protocols for perioperative analgesia in dogs undergoing TPLO surgery for the
treatment of a ruptured cruciate. Forty-eight dogs were included in the study.
The dogs were randomly assigned to receive one of the following protocols:
IM
premedication with morphine
CRI
of morphine, lidocaine, and ketamine (MLK)
Lumbosacral
epidural of morphine and ropivicaine
Both
MLK and the epidural of morphine and ropivicaine.
All dogs received NSAIDS after surgery.
Pain and sedation scores were collected from the dogs for 24 hours
postoperatively. Morphine was administered as a rescue analgesic if a pain
score of > 5 of 24 was determined.
No differences in anesthetic parameters
were found between groups, and no differences in postoperative pain parameters
(pain scores, sedation score, rescue analgesia requirement, or time to first
rescue analgesia administered after surgery) were found. The authors concluded
that all 4 analgesic protocols were acceptable for postoperative analgesia for
the first 24 hours.
Commentary
The most conservative analgesic
protocol, i.e., premedication with morphine alone, was as effective as the more
aggressive protocols. Based on the results of this study, the conservative
approach of an opiod premedication combined with postoperative NSAID therapy
appears to be an appropriate method of pain control in dogs having TPLO.
This well designed study provides us
with valuable clinical information. The authors chose dogs having TPLO, which
is a painful surgical procedure involving osteotomy of the proximal tibia
followed by plate fixation. The fact that 1 preoperative dose of morphine
combined with postoperative non-steroidal therapy provided acceptable
postoperative analgesia suggests that more aggressive pain management may not be
necessary.
The findings of this study bring up a
larger question: what is the appropriate
level of pain control for postoperative patients? How much analgesic
therapy is needed after other types of surgeries such as abdominal or thoracic
procedures? An aggressive approach to pain
management ensures that we are addressing the needs of the patient, however,
all medications have side effects and these must be considered when formulating
our approach. Regurgitation,
aspiration pneumonia, dysphoria and excessive sedation are all complications
that are associated with drugs used for analgesia. The subjective nature of our pain assessment methods makes
it difficult to know when we are administering an appropriate amount of
analgesia. Hopefully more studies like this one in which objective measures
were used to assess sedation and pain will be conducted to answer these
questions.
What is your opinion? What
routine analgesic protocols do you use and what is your experience with them? Leave
a comment on the blog or on facebook; I would love to hear your thoughts.